UniProt Summary: Isoform 2: Secreted protein may play a role in transcription regulation via the MAPK3/MAPK1 pathway through an unidentified receptor on the plasma membrane.
Pfam DomainsGO Terms
Pfam Domains
No Pfam Domain information is available for this gene.
GO Terms
negative regulation of ERK1 and ERK2 cascade
negative regulation of MAPK cascade
regulation of ERK1 and ERK2 cascade
negative regulation of protein phosphorylation
regulation of DNA-binding transcription factor activity
negative regulation of phosphorylation
negative regulation of intracellular signal transduction
negative regulation of phosphate metabolic process
negative regulation of phosphorus metabolic process
negative regulation of protein modification process
regulation of MAPK cascade
negative regulation of cellular protein metabolic process
negative regulation of protein metabolic process
negative regulation of signal transduction
negative regulation of cell communication
negative regulation of signaling
regulation of protein phosphorylation
regulation of phosphorylation
extracellular space
negative regulation of response to stimulus
regulation of phosphate metabolic process
regulation of phosphorus metabolic process
regulation of intracellular signal transduction
regulation of protein modification process
CRISPR Data
Compound HitMost Correlated Genes in ChemogenomicsTissues where Essential in the Avana Dataset (DepMap 20Q1)