CCDC66
Gene Information
- Official Symbol: CCDC66
- Official Name: coiled-coil domain containing 66
- Aliases and Previous Symbols: N/A
- Entrez ID: 285331
- UniProt: A2RUB6
- Interactions: BioGRID
- PubMed articles: Open PubMed
- OMIM: Open OMIM
Function Summary
- Entrez Summary: N/A
- UniProt Summary: N/A
Pfam Domains GO Terms
Pfam Domains
No Pfam Domain information is available for this gene.
GO Terms
| regulation of protein localization to cilium |
| retinal rod cell development |
| detection of light stimulus involved in sensory perception |
| detection of light stimulus involved in visual perception |
| ciliary transition zone |
| centriolar satellite |
| eye photoreceptor cell development |
| eye photoreceptor cell differentiation |
| photoreceptor cell development |
| detection of visible light |
| photoreceptor inner segment |
| photoreceptor cell differentiation |
| photoreceptor outer segment |
| detection of light stimulus |
| retina homeostasis |
| microtubule bundle formation |
| detection of external stimulus |
| detection of abiotic stimulus |
| ciliary basal body |
| eye morphogenesis |
| tissue homeostasis |
| cilium |
| visual perception |
| sensory perception of light stimulus |
| microtubule binding |
| sensory organ morphogenesis |
| response to light stimulus |
| microtubule |
| multicellular organismal homeostasis |
| anatomical structure homeostasis |
| cilium assembly |
| eye development |
| visual system development |
| sensory system development |
| cilium organization |
| response to radiation |
| plasma membrane bounded cell projection assembly |
| cell projection assembly |
| microtubule cytoskeleton organization |
| centrosome |
| regulation of cellular protein localization |
| detection of stimulus involved in sensory perception |
| sensory organ development |
| microtubule-based process |
| detection of stimulus |
| organelle assembly |
| neuron development |
| protein homodimerization activity |
| regulation of cellular localization |
| animal organ morphogenesis |
| sensory perception |
| neuron differentiation |
| regulation of protein localization |
| cytoskeleton organization |
| plasma membrane bounded cell projection organization |
| response to abiotic stimulus |
| cell projection organization |
| nervous system process |
| generation of neurons |
| neurogenesis |
| homeostatic process |
| cell development |
| system process |
CRISPR Data
Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)
Compound Hit
| Screen | Score |
|---|---|
| DKK1 89ng/ml R08 exp477 | 1.71 |
| Apcin 50 to 100μM on day4 R04 exp176 | 1.86 |
Most Correlated Genes in Chemogenomics
| Gene | Correlation |
|---|---|
| RRM1 | 0.408 |
Tissues where Essential in the Avana Dataset (DepMap 20Q1)
Global Fraction of Cell Lines Where Essential: 0/739
| Tissue | Fraction Of Cell Lines Where Essential |
|---|---|
| 1290807.0 | 0/1 |
| 909776.0 | 0/1 |
| bile duct | 0/28 |
| blood | 0/28 |
| bone | 0/26 |
| breast | 0/33 |
| central nervous system | 0/56 |
| cervix | 0/4 |
| colorectal | 0/17 |
| esophagus | 0/13 |
| fibroblast | 0/1 |
| gastric | 0/16 |
| kidney | 0/21 |
| liver | 0/20 |
| lung | 0/75 |
| lymphocyte | 0/16 |
| ovary | 0/26 |
| pancreas | 0/24 |
| peripheral nervous system | 0/16 |
| plasma cell | 0/15 |
| prostate | 0/1 |
| skin | 0/24 |
| soft tissue | 0/9 |
| thyroid | 0/2 |
| upper aerodigestive | 0/22 |
| urinary tract | 0/29 |
| uterus | 0/5 |
Essentiality in NALM6
- Essentiality Rank: 18008
- Expression level (log2 read counts): 6.04
Expression Distribution
CCDC66 Expression in NALM6 Cells: 6.04
