DKK1 89ng/ml R08 exp477
Mechanism of Action
Dickkopf1 (DKK1), recombinant protein inhibitor of WNT signaling, binds LRP5/LRP6 co-receptor and KRM1
- Class / Subclass 1: Signal Transduction / GPCR Antagonist
Technical Notes
Compound References
- PubChem Name: N/A
- Synonyms: N/A
- CAS #: N/A
- PubChem CID: N/A
- IUPAC: N/A
- INCHI Name: N/A
- INCHI Key: N/A
- Molecular Weight: 27.22kDa
- Canonical SMILES: N/A
- Isomeric SMILES: N/A
- Molecular Formula: Met 2-His 266
Compound Supplier
- Supplier Name: Sino Biological
- Catalog #: 10170-H08H
- Lot #: LC09DE3010
Compound Characterization
Characterization data not available.
Dose Response Curve
- Platform ID: DKK1
- Min: -7.2933; Max: 24.4479
| IC | Concentration (µM) |
|---|---|
| IC10 | N/A |
| IC20 | N/A |
| IC30 | N/A |
| IC40 | N/A |
| IC50 | N/A |
| IC60 | N/A |
| IC70 | N/A |
| IC80 | N/A |
| IC90 | N/A |
Screen Summary
- Round: 08
- Dose: 89ng/mL
- Days of incubation: 8
- Doublings: 7.1
- Numbers of reads: 16422937
Screen Results
| Sensitive/Resistant hits (FDR<0.05) | CRANKS | Score Plot | Top 30 Genes | Screen Similarity | Top 30 Sensitive GO terms | Top 30 Resistant GO terms |
|---|---|---|---|---|---|---|
| 0/0 | Scores |
DKK1 89ng/ml R08 exp477
