UniProt Summary: Positive regulator of neurite outgrowth by stabilizing myosin regulatory light chain (MRLC). It prevents MIR-mediated MRLC ubiquitination and its subsequent proteasomal degradation.
Pfam DomainsGO Terms
Pfam Domains
DUF3456
GO Terms
positive regulation of low-density lipoprotein particle receptor biosynthetic process
regulation of low-density lipoprotein particle receptor biosynthetic process
regulation of low-density lipoprotein particle clearance
positive regulation of receptor biosynthetic process
regulation of lipoprotein particle clearance
regulation of receptor biosynthetic process
endoplasmic reticulum
positive regulation of protein metabolic process
negative regulation of gene expression
positive regulation of macromolecule biosynthetic process
positive regulation of biosynthetic process
CRISPR Data
Compound HitMost Correlated Genes in ChemogenomicsTissues where Essential in the Avana Dataset (DepMap 20Q1)