CYP2W1
Gene Information
- Official Symbol: CYP2W1
- Official Name: cytochrome P450 family 2 subfamily W member 1
- Aliases and Previous Symbols: N/A
- Entrez ID: 54905
- UniProt: Q8TAV3
- Interactions: BioGRID
- PubMed articles: Open PubMed
- OMIM: Open OMIM
Function Summary
- Entrez Summary: This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. [provided by RefSeq, Jul 2008].
- UniProt Summary: Seems to have broad catalytic activity towards several chemicals, including polycyclic aromatic hydrocarbon dihydrodiols and aromatic amines (PubMed:16551781, PubMed:24278521). Active also in the metabolism of indoline substrates and is able to activate aflatoxin B1 into cytotoxic products (PubMed:20805301). Furthermore, it seems to be involved in the oxydation of lysophospholipids and fatty acids (PubMed:22591743). {ECO:0000269|PubMed:16551781, ECO:0000269|PubMed:20805301, ECO:0000269|PubMed:22591743, ECO:0000269|PubMed:24278521}.
CRISPR Data
Essentiality in NALM6
- Essentiality Rank: 9810
- Expression level (log2 read counts): 0.06
CYP2W1 Expression in NALM6 Cells: 0.06
