DDX18

Pfam Domains GO Terms

Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)

Screen	Score
UM131593 0.2μM R03 exp106	-2.11
JQ1 0.8μM R08 exp435	-1.96
Actinomycin-D 0.01μM R00 exp4	-1.78
Salinomycin 3.5μM R08 exp521	-1.73
SB743921 0.001μM R05 exp244	-1.71
Vinblastine 0.002μM R01 exp60	-1.71
CoCl2 18μM R07 exp346	1.74
Losmapimod 1μM R07 exp376	1.82
Bisphenol S 100μM R08 exp458	2.03
LY2090314 0.003μM R08 exp499	2.08
THZ531 0.11 to 0.125μM on day4 R07 exp410	2.12
ABT-702 5μM R07 exp318	2.2
THZ531 0.11 to 0.125 to 0.35μM on day4 then day6 R07 exp412	2.33

Global Fraction of Cell Lines Where Essential: 292/739

Tissue	Fraction Of Cell Lines Where Essential
1290807.0	1/1
909776.0	0/1
bile duct	10/28
blood	5/28
bone	6/26
breast	16/33
central nervous system	25/56
cervix	2/4
colorectal	8/17
esophagus	8/13
fibroblast	1/1
gastric	6/16
kidney	9/21
liver	5/20
lung	29/75
lymphocyte	5/16
ovary	7/26
pancreas	5/24
peripheral nervous system	4/16
plasma cell	9/15
prostate	1/1
skin	10/24
soft tissue	3/9
thyroid	0/2
upper aerodigestive	8/22
urinary tract	16/29
uterus	2/5

Expression Distribution