EMC10
Gene Information
- Official Symbol: EMC10
- Official Name: ER membrane protein complex subunit 10
- Aliases and Previous Symbols: N/A
- Entrez ID: 284361
- UniProt: Q5UCC4
- Interactions: BioGRID
- PubMed articles: Open PubMed
- OMIM: Open OMIM
Function Summary
- Entrez Summary: N/A
- UniProt Summary: N/A
Pfam Domains GO Terms
Pfam Domains
No Pfam Domain information is available for this gene.
GO Terms
| ER membrane protein complex |
| positive regulation of p38MAPK cascade |
| regulation of p38MAPK cascade |
| positive regulation of endothelial cell proliferation |
| positive regulation of endothelial cell migration |
| regulation of endothelial cell proliferation |
| positive regulation of epithelial cell migration |
| regulation of endothelial cell migration |
| positive regulation of angiogenesis |
| positive regulation of stress-activated MAPK cascade |
| positive regulation of stress-activated protein kinase signaling cascade |
| positive regulation of vasculature development |
| positive regulation of epithelial cell proliferation |
| regulation of epithelial cell migration |
| regulation of stress-activated MAPK cascade |
| regulation of stress-activated protein kinase signaling cascade |
| regulation of angiogenesis |
| angiogenesis |
| regulation of vasculature development |
| regulation of epithelial cell proliferation |
| blood vessel morphogenesis |
| blood vessel development |
| positive regulation of cell migration |
| vasculature development |
| cardiovascular system development |
| positive regulation of cell motility |
| positive regulation of cellular component movement |
| positive regulation of MAPK cascade |
| positive regulation of locomotion |
| tube morphogenesis |
| regulation of cellular response to stress |
| regulation of MAPK cascade |
| tube development |
| regulation of cell migration |
| circulatory system development |
| anatomical structure formation involved in morphogenesis |
| regulation of cell motility |
| positive regulation of cell population proliferation |
| regulation of locomotion |
| regulation of cellular component movement |
| positive regulation of protein phosphorylation |
| positive regulation of intracellular signal transduction |
| positive regulation of phosphorylation |
| regulation of anatomical structure morphogenesis |
| positive regulation of phosphorus metabolic process |
| positive regulation of phosphate metabolic process |
| positive regulation of protein modification process |
| positive regulation of developmental process |
| regulation of protein phosphorylation |
| regulation of response to stress |
| regulation of phosphorylation |
| positive regulation of cellular protein metabolic process |
| regulation of cell population proliferation |
| positive regulation of signal transduction |
| positive regulation of protein metabolic process |
| positive regulation of multicellular organismal process |
| regulation of phosphate metabolic process |
| regulation of phosphorus metabolic process |
| positive regulation of cell communication |
| positive regulation of signaling |
| regulation of intracellular signal transduction |
| regulation of protein modification process |
| extracellular region |
CRISPR Data
Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)
Compound Hit
| Screen | Score |
|---|---|
| VER-155008 3.9μM R06 exp301 | -2.07 |
| ABT-702 5μM R06 exp261 | -1.88 |
| Phorbol-12-myristate-13-acetate 0.57μM R08 exp514 | 1.73 |
| ETC-159 50μM R08 exp480 | 1.79 |
Most Correlated Genes in Chemogenomics
| Gene | Correlation |
|---|---|
| HGC6.3 | 0.567 |
Tissues where Essential in the Avana Dataset (DepMap 20Q1)
Global Fraction of Cell Lines Where Essential: 0/739
| Tissue | Fraction Of Cell Lines Where Essential |
|---|---|
| 1290807.0 | 0/1 |
| 909776.0 | 0/1 |
| bile duct | 0/28 |
| blood | 0/28 |
| bone | 0/26 |
| breast | 0/33 |
| central nervous system | 0/56 |
| cervix | 0/4 |
| colorectal | 0/17 |
| esophagus | 0/13 |
| fibroblast | 0/1 |
| gastric | 0/16 |
| kidney | 0/21 |
| liver | 0/20 |
| lung | 0/75 |
| lymphocyte | 0/16 |
| ovary | 0/26 |
| pancreas | 0/24 |
| peripheral nervous system | 0/16 |
| plasma cell | 0/15 |
| prostate | 0/1 |
| skin | 0/24 |
| soft tissue | 0/9 |
| thyroid | 0/2 |
| upper aerodigestive | 0/22 |
| urinary tract | 0/29 |
| uterus | 0/5 |
Essentiality in NALM6
- Essentiality Rank: 12770
- Expression level (log2 read counts): 6.89
Expression Distribution
EMC10 Expression in NALM6 Cells: 6.89
