EXOC8
Gene Information
- Official Symbol: EXOC8
- Official Name: exocyst complex component 8
- Aliases and Previous Symbols: N/A
- Entrez ID: 149371
- UniProt: Q8IYI6
- Interactions: BioGRID
- PubMed articles: Open PubMed
- OMIM: Open OMIM
Function Summary
- Entrez Summary: This gene encodes a component of the exocyst complex, an evolutionarily conserved multi-protein complex that plays a critical role in vesicular trafficking and the secretory pathway by targeting post-Golgi vesicles to the plasma membrane. This protein is a target of activated Ral subfamily of GTPases and thereby regulates exocytosis by tethering vesicles to the plasma membrane. Mutations in this gene may be related to Joubert syndrome. [provided by RefSeq, Sep 2016].
- UniProt Summary: Component of the exocyst complex involved in the docking of exocytic vesicles with fusion sites on the plasma membrane.
CRISPR Data
Essentiality in NALM6
- Essentiality Rank: 2327
- Expression level (log2 read counts): 5.51
EXOC8 Expression in NALM6 Cells: 5.51
