FABP2
Gene Information
- Official Symbol: FABP2
- Official Name: fatty acid binding protein 2
- Aliases and Previous Symbols: N/A
- Entrez ID: 2169
- UniProt: P12104
- Interactions: BioGRID
- PubMed articles: Open PubMed
- OMIM: Open OMIM
Function Summary
- Entrez Summary: The protein encoded by this gene is an intracellular fatty acid-binding protein that participates in the uptake, intracellular metabolism, and transport of long-chain fatty acids. The encoded protein is also involved in the modulation of cell growth and proliferation. This protein binds saturated long-chain fatty acids with high affinity, and may act as a lipid sensor to maintain energy homeostasis. [provided by RefSeq, Aug 2017].
- UniProt Summary: FABP are thought to play a role in the intracellular transport of long-chain fatty acids and their acyl-CoA esters. FABP2 is probably involved in triglyceride-rich lipoprotein synthesis. Binds saturated long-chain fatty acids with a high affinity, but binds with a lower affinity to unsaturated long- chain fatty acids. FABP2 may also help maintain energy homeostasis by functioning as a lipid sensor.
CRISPR Data
Essentiality in NALM6
- Essentiality Rank: 10329
- Expression level (log2 read counts): 1.25
FABP2 Expression in NALM6 Cells: 1.25
