FILIP1
Gene Information
- Official Symbol: FILIP1
- Official Name: filamin A interacting protein 1
- Aliases and Previous Symbols: N/A
- Entrez ID: 27145
- UniProt: Q7Z7B0
- Interactions: BioGRID
- PubMed articles: Open PubMed
- OMIM: Open OMIM
Function Summary
- Entrez Summary: This gene encodes a filamin A binding protein. The encoded protein promotes the degradation of filamin A and may regulate cortical neuron migration and dendritic spine morphology. Mice lacking a functional copy of this gene exhibit reduced dendritic spine length and altered excitatory signaling. [provided by RefSeq, Oct 2016].
- UniProt Summary: By acting through a filamin-A/F-actin axis, it controls the start of neocortical cell migration from the ventricular zone. May be able to induce the degradation of filamin-A. {ECO:0000250|UniProtKB:Q8K4T4}.
CRISPR Data
Essentiality in NALM6
- Essentiality Rank: 8366
- Expression level (log2 read counts): 1.55
FILIP1 Expression in NALM6 Cells: 1.55
