Entrez Summary: This gene encodes a member of the G protein-coupled receptor family described as an epididymis-specific transmembrane protein. The encoded protein may be proteolytically processed as it contains a motif shown to be a protein scission motif in some members of this family (PMID: 11973329). Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Aug 2011].
UniProt Summary: N/A
Pfam DomainsGO Terms
Pfam Domains
GPS
7tm 2
GO Terms
adenylate cyclase-activating G protein-coupled receptor signaling pathway
cAMP-mediated signaling
cyclic-nucleotide-mediated signaling
adenylate cyclase-modulating G protein-coupled receptor signaling pathway
G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger
apical plasma membrane
second-messenger-mediated signaling
spermatogenesis
male gamete generation
cell surface
gamete generation
G protein-coupled receptor activity
multicellular organismal reproductive process
sexual reproduction
multicellular organism reproduction
multi-organism reproductive process
G protein-coupled receptor signaling pathway
integral component of plasma membrane
reproductive process
reproduction
intracellular signal transduction
CRISPR Data
Compound HitMost Correlated Genes in ChemogenomicsTissues where Essential in the Avana Dataset (DepMap 20Q1)