UniProt Summary: Postsynaptic scaffolding protein at the parallel fiber- Purkinje cell synapse, where it may serve to link GRID2 with actin cytoskeleton and various signaling molecules. {ECO:0000250}.
Pfam DomainsGO Terms
Pfam Domains
FH2
PDZ
GO Terms
long-term synaptic depression
negative regulation of synaptic transmission
regulation of synaptic plasticity
postsynaptic membrane
modulation of chemical synaptic transmission
regulation of trans-synaptic signaling
cell junction
negative regulation of cell communication
negative regulation of signaling
CRISPR Data
Compound HitMost Correlated Genes in ChemogenomicsTissues where Essential in the Avana Dataset (DepMap 20Q1)