KANSL2

Entrez Summary: N/A
UniProt Summary: As part of the NSL complex it is involved in acetylation of nucleosomal histone H4 on several lysine residues and therefore may be involved in the regulation of transcription. {ECO:0000269|PubMed:20018852}.

Pfam Domains GO Terms

Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)

Screen	Score
Nocodazole 0.2μM R02 exp64	-2.08
Salinomycin 3.5μM R08 exp521	-2.06
SNS-032 25μM R07 exp401	-1.94
ABT-702 5μM plus Deferoxamine 11μM R07 exp321	-1.9
DABN 20μM R00 exp17	-1.89
Oligomycin-A 20μM R00 exp26	-1.79
Thioridazine 5μM R08 exp530	1.76
Radicicol 0.16μM R05 exp242	1.87
UNC1999 2μM R03 exp155	1.92
Hippuristanol 0.12μM R08 exp488	1.93
Tunicamycin 0.04 to 0.075μM on day4 R07 exp419	1.96
Prochlorperazine 5.2μM R02 exp77	1.99
A-395 10μM R05 exp218	2.05
Fas-L 44ng/ml R08 exp482	2.2

Global Fraction of Cell Lines Where Essential: 77/726

Tissue	Fraction Of Cell Lines Where Essential
1290807.0	0/1
909776.0	0/1
bile duct	0/28
blood	6/28
bone	5/25
breast	2/33
central nervous system	6/56
cervix	0/4
colorectal	1/17
esophagus	0/13
fibroblast	0/1
gastric	1/15
kidney	5/21
liver	2/20
lung	8/75
lymphocyte	3/14
ovary	5/26
pancreas	3/24
peripheral nervous system	3/16
plasma cell	0/15
prostate	0/1
skin	1/24
soft tissue	1/7
thyroid	0/2
upper aerodigestive	0/22
urinary tract	3/29
uterus	1/5

Expression Distribution