MAL2

Gene Information

Official Symbol: MAL2
Official Name: mal, T cell differentiation protein 2 (gene/pseudogene)
Aliases and Previous Symbols: N/A
Entrez ID: 114569
UniProt: Q969L2
Interactions: BioGRID
PubMed articles: Open PubMed
OMIM: Open OMIM

Function Summary

Entrez Summary: N/A
UniProt Summary: Member of the machinery of polarized transport. Required for the indirect transcytotic route at the step of the egress of the transcytosing cargo from perinuclear endosomes in order for it to travel to the apical surface via a raft-dependent pathway. {ECO:0000269|PubMed:12370246}.

Pfam Domains GO Terms

CRISPR Data

Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)

Screen	Score
Ribavirin 10μM R01 exp52	-2.46
A-366 10μM R03 exp115	-1.88
LLY-284 2.6μM R06 exp291	-1.78
PF-06409577 20μM R07 exp389	-1.71
Rapamycin 1μM R00 exp29	1.85
Nifuroxazide 1μM R01 exp51	1.88

Essentiality in NALM6

Essentiality Rank: 18928
Expression level (log2 read counts): -2.21

Expression Distribution