UniProt Summary: Involved in organization of the bipolar mitotic spindle. Required for bipolar spindle assembly, mitosis progression and cytokinesis. May act by stabilizing interphase microtubules. {ECO:0000269|PubMed:16049101}.
Pfam DomainsGO Terms
Pfam Domains
No Pfam Domain information is available for this gene.
GO Terms
astral microtubule
regulation of mitotic cytokinesis
regulation of mitotic centrosome separation
mitotic spindle midzone
spindle midzone
mitotic spindle assembly
regulation of mitotic spindle organization
regulation of spindle organization
regulation of centrosome cycle
mitotic cytokinesis
mitotic spindle organization
mitotic spindle
regulation of cytokinesis
cytoskeleton-dependent cytokinesis
cytokinesis
spindle assembly
microtubule cytoskeleton organization involved in mitosis
mitotic nuclear division
spindle organization
regulation of mitotic nuclear division
regulation of cell division
regulation of microtubule cytoskeleton organization
regulation of nuclear division
regulation of microtubule-based process
microtubule binding
nuclear division
axon
organelle fission
microtubule cytoskeleton organization
cell division
regulation of cytoskeleton organization
mitotic cell cycle process
regulation of mitotic cell cycle
microtubule-based process
mitotic cell cycle
regulation of cell cycle process
organelle assembly
cell cycle process
cytoskeleton organization
regulation of cell cycle
regulation of organelle organization
cell cycle
CRISPR Data
Compound HitMost Correlated Genes in ChemogenomicsTissues where Essential in the Avana Dataset (DepMap 20Q1)