MED11
Gene Information
- Official Symbol: MED11
- Official Name: mediator complex subunit 11
- Aliases and Previous Symbols: N/A
- Entrez ID: 400569
- UniProt: Q9P086
- Interactions: BioGRID
- PubMed articles: Open PubMed
- OMIM: Open OMIM
Function Summary
- Entrez Summary: N/A
- UniProt Summary: Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.
CRISPR Data
Essentiality in NALM6
- Essentiality Rank: 1040
- Expression level (log2 read counts): 3.9
MED11 Expression in NALM6 Cells: 3.9
