MSMO1
Gene Information
- Official Symbol: MSMO1
- Official Name: methylsterol monooxygenase 1
- Aliases and Previous Symbols: N/A
- Entrez ID: 6307
- UniProt: Q15800
- Interactions: BioGRID
- PubMed articles: Open PubMed
- OMIM: Open OMIM
Function Summary
- Entrez Summary: Sterol-C4-mehtyl oxidase-like protein was isolated based on its similarity to the yeast ERG25 protein. It contains a set of putative metal binding motifs with similarity to that seen in a family of membrane desaturases-hydroxylases. The protein is localized to the endoplasmic reticulum membrane and is believed to function in cholesterol biosynthesis. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq, Jul 2008].
- UniProt Summary: Catalyzes the first step in the removal of the two C-4 methyl groups of 4,4-dimethylzymosterol. {ECO:0000250|UniProtKB:P53045}.
CRISPR Data
Essentiality in NALM6
- Essentiality Rank: 16473
- Expression level (log2 read counts): 5.8
MSMO1 Expression in NALM6 Cells: 5.8
