Pfam Domains GO Terms
| mitotic chromosome condensation |
| establishment of mitotic spindle localization |
| spindle microtubule |
| establishment of spindle localization |
| chromosome condensation |
| spindle localization |
| positive regulation of mitotic nuclear division |
| positive regulation of nuclear division |
| mitotic cytokinesis |
| mitotic spindle |
| cytoskeleton-dependent cytokinesis |
| cytokinesis |
| microtubule cytoskeleton organization involved in mitosis |
| mitotic sister chromatid segregation |
| chromosome |
| sister chromatid segregation |
| mitotic nuclear division |
| positive regulation of mitotic cell cycle |
| regulation of mitotic nuclear division |
| DNA packaging |
| regulation of nuclear division |
| nuclear chromosome segregation |
| microtubule binding |
| chromosome segregation |
| nuclear division |
| positive regulation of cell cycle process |
| DNA conformation change |
| organelle fission |
| establishment of organelle localization |
| positive regulation of cell cycle |
| microtubule cytoskeleton organization |
| cell division |
| organelle localization |
| mitotic cell cycle process |
| positive regulation of organelle organization |
| regulation of mitotic cell cycle |
| microtubule-based process |
| mitotic cell cycle |
| regulation of cell cycle process |
| nucleolus |
| cell cycle process |
| chromosome organization |
| cytoskeleton organization |
| regulation of cell cycle |
| positive regulation of cellular component organization |
| regulation of organelle organization |
| cell cycle |
| RNA binding |
| DNA binding |
| establishment of localization in cell |
Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)
| Screen | Score |
|---|---|
| UMK57 1μM R01 exp59 | -2.13 |
| Mdivi-1 15μM R05 exp217 | -1.87 |
| Menadione 5μM R06 exp292 | 1.76 |
| All-trans-Retinoic-Acid 40μM R07 exp334 | 2.05 |
| BI-2536 0.0042μM R03 exp95 | 2.28 |
| Tissue | Fraction Of Cell Lines Where Essential |
|---|---|
| 1290807.0 | 0/1 |
| 909776.0 | 0/1 |
| bile duct | 0/28 |
| blood | 0/28 |
| bone | 0/26 |
| breast | 0/33 |
| central nervous system | 0/56 |
| cervix | 0/4 |
| colorectal | 0/17 |
| esophagus | 0/13 |
| fibroblast | 0/1 |
| gastric | 0/16 |
| kidney | 0/21 |
| liver | 0/20 |
| lung | 0/75 |
| lymphocyte | 0/16 |
| ovary | 0/26 |
| pancreas | 0/24 |
| peripheral nervous system | 0/16 |
| plasma cell | 0/15 |
| prostate | 0/1 |
| skin | 0/24 |
| soft tissue | 0/9 |
| thyroid | 0/2 |
| upper aerodigestive | 0/22 |
| urinary tract | 0/29 |
| uterus | 0/5 |
Expression Distribution