PKD1L3
Gene Information
- Official Symbol: PKD1L3
- Official Name: polycystin 1 like 3, transient receptor potential channel interacting
- Aliases and Previous Symbols: N/A
- Entrez ID: 342372
- UniProt: Q7Z443
- Interactions: BioGRID
- PubMed articles: Open PubMed
- OMIM: Open OMIM
Function Summary
- Entrez Summary: This gene encodes a member of the polycystin protein family. The encoded protein contains 11 transmembrane domains, a latrophilin/CL-1-like GPCR proteolytic site (GPS) domain, and a polycystin-1, lipoxygenase, alpha-toxin (PLAT) domain. This protein may function as a component of cation channel pores.[provided by RefSeq, Apr 2009].
- UniProt Summary: Component of a calcium channel. May act as a sour taste receptor by forming a calcium channel with PKD1L3 in gustatory cells; however, its contribution to sour taste perception is unclear in vivo and may be indirect. {ECO:0000269|PubMed:12782129, ECO:0000269|PubMed:19812697, ECO:0000269|PubMed:23212381}.
CRISPR Data
Essentiality in NALM6
- Essentiality Rank: 12718
- Expression level (log2 read counts): -2.38
PKD1L3 Expression in NALM6 Cells: -2.38
