RBM5
Gene Information
- Official Symbol: RBM5
- Official Name: RNA binding motif protein 5
- Aliases and Previous Symbols: N/A
- Entrez ID: 10181
- UniProt: P52756
- Interactions: BioGRID
- PubMed articles: Open PubMed
- OMIM: Open OMIM
Function Summary
- Entrez Summary: This gene is a candidate tumor suppressor gene which encodes a nuclear RNA binding protein that is a component of the spliceosome A complex. The encoded protein plays a role in the induction of cell cycle arrest and apoptosis through pre-mRNA splicing of multiple target genes including the tumor suppressor protein p53. This gene is located within the tumor suppressor region 3p21.3, and may play a role in the inhibition of tumor transformation and progression of several malignancies including lung cancer. [provided by RefSeq, Oct 2011].
- UniProt Summary: N/A
CRISPR Data
Essentiality in NALM6
- Essentiality Rank: 7618
- Expression level (log2 read counts): 8.07
RBM5 Expression in NALM6 Cells: 8.07
