RCN3
Gene Information
- Official Symbol: RCN3
- Official Name: reticulocalbin 3
- Aliases and Previous Symbols: N/A
- Entrez ID: 57333
- UniProt: Q96D15
- Interactions: BioGRID
- PubMed articles: Open PubMed
- OMIM: Open OMIM
Function Summary
- Entrez Summary: N/A
- UniProt Summary: N/A
Pfam Domains GO Terms
Pfam Domains
No Pfam Domain information is available for this gene.
GO Terms
| collagen biosynthetic process |
| phospholipid homeostasis |
| surfactant homeostasis |
| chemical homeostasis within a tissue |
| lung epithelium development |
| anion homeostasis |
| collagen metabolic process |
| ERAD pathway |
| lipid homeostasis |
| protein secretion |
| establishment of protein localization to extracellular region |
| protein localization to extracellular region |
| lung development |
| respiratory tube development |
| peptide secretion |
| tissue homeostasis |
| positive regulation of peptidase activity |
| respiratory system development |
| regulation of protein kinase B signaling |
| response to endoplasmic reticulum stress |
| endoplasmic reticulum lumen |
| multicellular organismal homeostasis |
| anatomical structure homeostasis |
| proteasomal protein catabolic process |
| positive regulation of proteolysis |
| regulation of peptidase activity |
| proteolysis involved in cellular protein catabolic process |
| cellular protein catabolic process |
| protein catabolic process |
| calcium ion binding |
| regulation of proteolysis |
| positive regulation of hydrolase activity |
| ion homeostasis |
| tube development |
| cellular macromolecule catabolic process |
| response to organonitrogen compound |
| secretion by cell |
| endoplasmic reticulum |
| export from cell |
| macromolecule catabolic process |
| organonitrogen compound catabolic process |
| response to nitrogen compound |
| chemical homeostasis |
| epithelium development |
| secretion |
| proteolysis |
| regulation of hydrolase activity |
| positive regulation of catalytic activity |
| protein transport |
| peptide transport |
| amide transport |
| positive regulation of cellular protein metabolic process |
| establishment of protein localization |
| homeostatic process |
| cellular response to stress |
| positive regulation of protein metabolic process |
| tissue development |
| organic substance catabolic process |
| positive regulation of molecular function |
| cellular catabolic process |
| regulation of intracellular signal transduction |
| nitrogen compound transport |
CRISPR Data
Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)
Compound Hit
| Screen | Score |
|---|---|
| TRAIL 5ng/ml R00 exp35 | -1.73 |
| Cidofovir 10μM R07 exp345 | 1.73 |
Most Correlated Genes in Chemogenomics
No correlation found to any other genes in chemogenomics.
Tissues where Essential in the Avana Dataset (DepMap 20Q1)
Global Fraction of Cell Lines Where Essential: 0/739
| Tissue | Fraction Of Cell Lines Where Essential |
|---|---|
| 1290807.0 | 0/1 |
| 909776.0 | 0/1 |
| bile duct | 0/28 |
| blood | 0/28 |
| bone | 0/26 |
| breast | 0/33 |
| central nervous system | 0/56 |
| cervix | 0/4 |
| colorectal | 0/17 |
| esophagus | 0/13 |
| fibroblast | 0/1 |
| gastric | 0/16 |
| kidney | 0/21 |
| liver | 0/20 |
| lung | 0/75 |
| lymphocyte | 0/16 |
| ovary | 0/26 |
| pancreas | 0/24 |
| peripheral nervous system | 0/16 |
| plasma cell | 0/15 |
| prostate | 0/1 |
| skin | 0/24 |
| soft tissue | 0/9 |
| thyroid | 0/2 |
| upper aerodigestive | 0/22 |
| urinary tract | 0/29 |
| uterus | 0/5 |
Essentiality in NALM6
- Essentiality Rank: 7079
- Expression level (log2 read counts): -2.43
Expression Distribution
RCN3 Expression in NALM6 Cells: -2.43
