RTFDC1

Gene Information

Official Symbol: RTF2
Official Name: replication termination factor 2
Aliases and Previous Symbols: N/A
Entrez ID: 51507
UniProt: Q9BY42
Interactions: BioGRID
PubMed articles: Open PubMed
OMIM: N/A

Function Summary

Entrez Summary: N/A
UniProt Summary: N/A

Pfam Domains GO Terms

CRISPR Data

Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)

Screen	Score
Arsenate 40μM R06 exp264	-2.76
Fluvastatin 2.2μM R06 exp282	-2.15
ABT-702 0.1μM R06 exp260	-1.85
Radicicol 0.16μM R05 exp242	-1.83
Talazoparib 0.006μM R06 exp299	-1.81
LJH685 50μM R08 exp433	-1.76
Q15 2.7μM R02 exp79	-1.76
CI-1040 9.5μM R08 exp472	-1.75
LLY-283 2.6μM R06 exp290	-1.7
2-Methoxyestradiol 0.2μM R01 exp40	1.81

Global Fraction of Cell Lines Where Essential: 143/739

Tissue	Fraction Of Cell Lines Where Essential
1290807.0	0/1
909776.0	0/1
bile duct	7/28
blood	10/28
bone	7/26
breast	5/33
central nervous system	17/56
cervix	0/4
colorectal	0/17
esophagus	0/13
fibroblast	0/1
gastric	0/16
kidney	2/21
liver	4/20
lung	16/75
lymphocyte	4/16
ovary	5/26
pancreas	3/24
peripheral nervous system	4/16
plasma cell	7/15
prostate	0/1
skin	1/24
soft tissue	2/9
thyroid	0/2
upper aerodigestive	1/22
urinary tract	6/29
uterus	2/5

Essentiality in NALM6

Essentiality Rank: 1105
Expression level (log2 read counts): 5.84

Expression Distribution