UniProt Summary: May function as calcium sensor and modulator, contributing to cellular calcium signaling. May function by interacting with other proteins, such as TPR-containing proteins, and indirectly play a role in many physiological processes. May also play a role in suppressing tumor cell growth. {ECO:0000269|PubMed:1372446, ECO:0000269|PubMed:22399290}.
Pfam DomainsGO Terms
Pfam Domains
S 100
GO Terms
transition metal ion binding
endothelial cell migration
epithelial cell migration
epithelium migration
tissue migration
ameboidal-type cell migration
cellular component
calcium ion binding
cell migration
identical protein binding
cell motility
localization of cell
locomotion
movement of cell or subcellular component
CRISPR Data
Compound HitMost Correlated Genes in ChemogenomicsTissues where Essential in the Avana Dataset (DepMap 20Q1)