Pfam Domains GO Terms
| ciliary receptor clustering involved in smoothened signaling pathway |
| receptor clustering |
| intraciliary transport |
| protein transport along microtubule |
| microtubule-based protein transport |
| smoothened signaling pathway |
| localization within membrane |
| ciliary basal body-plasma membrane docking |
| G2/M transition of mitotic cell cycle |
| cell cycle G2/M phase transition |
| ciliary basal body |
| transport along microtubule |
| organelle localization by membrane tethering |
| cytoskeleton-dependent intracellular transport |
| membrane docking |
| microtubule-based transport |
| regulation of G2/M transition of mitotic cell cycle |
| regulation of cell cycle G2/M phase transition |
| protein-containing complex localization |
| mitotic cell cycle phase transition |
| microtubule-based movement |
| cell cycle phase transition |
| cilium assembly |
| cilium organization |
| regulation of mitotic cell cycle phase transition |
| plasma membrane bounded cell projection assembly |
| regulation of cell cycle phase transition |
| cell projection assembly |
| protein localization to membrane |
| centrosome |
| organelle localization |
| mitotic cell cycle process |
| regulation of mitotic cell cycle |
| microtubule-based process |
| mitotic cell cycle |
| regulation of cell cycle process |
| organelle assembly |
| intracellular protein transport |
| cell cycle process |
| identical protein binding |
| plasma membrane bounded cell projection organization |
| cell projection organization |
| regulation of cell cycle |
| cell cycle |
| protein transport |
| intracellular transport |
| peptide transport |
| movement of cell or subcellular component |
| amide transport |
| cellular protein localization |
| cellular macromolecule localization |
| establishment of protein localization |
| establishment of localization in cell |
| nitrogen compound transport |
Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)
| Screen | Score |
|---|---|
| Ethanol 0.01 R05 exp234 | 1.77 |
| Latrunculin-B 10μM R07 exp374 | 2.04 |
| Tissue | Fraction Of Cell Lines Where Essential |
|---|---|
| 1290807.0 | 0/1 |
| 909776.0 | 0/1 |
| bile duct | 0/28 |
| blood | 0/28 |
| bone | 0/26 |
| breast | 0/33 |
| central nervous system | 0/56 |
| cervix | 0/4 |
| colorectal | 0/17 |
| esophagus | 0/13 |
| fibroblast | 0/1 |
| gastric | 0/16 |
| kidney | 0/21 |
| liver | 0/20 |
| lung | 0/75 |
| lymphocyte | 0/16 |
| ovary | 0/26 |
| pancreas | 0/24 |
| peripheral nervous system | 0/16 |
| plasma cell | 0/15 |
| prostate | 0/1 |
| skin | 0/24 |
| soft tissue | 0/9 |
| thyroid | 0/2 |
| upper aerodigestive | 0/22 |
| urinary tract | 0/29 |
| uterus | 0/5 |
Expression Distribution