UniProt Summary: Acts as a positive regulator of apoptosis. Also acts as a regulator of cellular reactive oxygen species. {ECO:0000269|PubMed:21489989, ECO:0000269|PubMed:9786912}.
Pfam DomainsGO Terms
Pfam Domains
Pkinase
Pkinase Tyr
GO Terms
positive regulation of fibroblast apoptotic process
regulation of fibroblast apoptotic process
regulation of reactive oxygen species metabolic process
protein serine/threonine kinase activity
nuclear speck
positive regulation of apoptotic process
positive regulation of programmed cell death
positive regulation of cell death
apoptotic process
protein phosphorylation
programmed cell death
cell death
phosphorylation
ATP binding
regulation of apoptotic process
regulation of programmed cell death
regulation of cell death
intracellular signal transduction
CRISPR Data
Compound HitMost Correlated Genes in ChemogenomicsTissues where Essential in the Avana Dataset (DepMap 20Q1)