UniProt Summary: Gustducin-coupled receptor implicated in the perception of bitter compounds in the oral cavity and the gastrointestinal tract. Signals through PLCB2 and the calcium-regulated cation channel TRPM5. {ECO:0000269|PubMed:10761934, ECO:0000269|PubMed:10761935}.
Pfam DomainsGO Terms
Pfam Domains
TAS2R
GO Terms
taste receptor activity
bitter taste receptor activity
detection of chemical stimulus involved in sensory perception of bitter taste
sensory perception of bitter taste
detection of chemical stimulus involved in sensory perception of taste
sensory perception of taste
detection of chemical stimulus involved in sensory perception
detection of chemical stimulus
sensory perception of chemical stimulus
detection of stimulus involved in sensory perception
detection of stimulus
G protein-coupled receptor activity
sensory perception
G protein-coupled receptor signaling pathway
nervous system process
system process
CRISPR Data
Compound HitMost Correlated Genes in ChemogenomicsTissues where Essential in the Avana Dataset (DepMap 20Q1)