TCEAL4

Entrez Summary: This gene encodes a member of the transcription elongation factor A (SII)-like (TCEAL) gene family. This family is comprised of nuclear phosphoproteins that modulate transcription in a promoter context-dependent manner. Multiple family members are located on the X chromosome. Alternatively splicing results in multiple transcript variants. There is a pseudogene for this gene on chromosome 13. [provided by RefSeq, Apr 2015].
UniProt Summary: May be involved in transcriptional regulation.

Pfam Domains GO Terms

Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)

Screen	Score
Rotenone 0.07μM R08 exp431	-2.04
GSK-J4 1.5μM R08 exp441	-1.99
Aphidicolin 0.4μM R08 exp440	-1.96
MSC2530818 10μM R07 exp379	-1.87
Lead acetate 2000μM R08 exp498 no dilution day6	-1.78
Tanespimycin 14μM R08 exp527	-1.78
UNC1999 2μM R03 exp155	1.7
SGC2043 10μM R03 exp152	1.71
GSK343 3μM R03 exp124	1.82

Global Fraction of Cell Lines Where Essential: 0/683

Tissue	Fraction Of Cell Lines Where Essential
1290807.0	0/1
909776.0	0/1
bile duct	0/28
blood	0/26
bone	0/25
breast	0/30
central nervous system	0/49
cervix	0/4
colorectal	0/17
esophagus	0/11
fibroblast	0/1
gastric	0/14
kidney	0/18
liver	0/19
lung	0/72
lymphocyte	0/14
ovary	0/25
pancreas	0/22
peripheral nervous system	0/15
plasma cell	0/12
prostate	0/1
skin	0/20
soft tissue	0/7
thyroid	0/2
upper aerodigestive	0/22
urinary tract	0/28
uterus	0/5

Expression Distribution