TTC8
Gene Information
- Official Symbol: TTC8
- Official Name: tetratricopeptide repeat domain 8
- Aliases and Previous Symbols: N/A
- Entrez ID: 123016
- UniProt: Q8TAM2
- Interactions: BioGRID
- PubMed articles: Open PubMed
- OMIM: Open OMIM
Function Summary
- Entrez Summary: This gene encodes a protein that has been directly linked to Bardet-Biedl syndrome. The primary features of this syndrome include retinal dystrophy, obesity, polydactyly, renal abnormalities and learning disabilities. Experimentation in non-human eukaryotes suggests that this gene is expressed in ciliated cells and that it is involved in the formation of cilia. A mutation in this gene has also been implicated in nonsyndromic retinitis pigmentosa. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2014].
- UniProt Summary: N/A
CRISPR Data
Essentiality in NALM6
- Essentiality Rank: 14094
- Expression level (log2 read counts): 3.22
TTC8 Expression in NALM6 Cells: 3.22
