TUBB4B

Entrez Summary: N/A
UniProt Summary: Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain.

Pfam Domains GO Terms

Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)

Gene	Correlation
VBP1	0.437
SKA1	0.405

Global Fraction of Cell Lines Where Essential: 39/739

Tissue	Fraction Of Cell Lines Where Essential
1290807.0	0/1
909776.0	0/1
bile duct	5/28
blood	1/28
bone	0/26
breast	1/33
central nervous system	1/56
cervix	0/4
colorectal	2/17
esophagus	1/13
fibroblast	0/1
gastric	2/16
kidney	1/21
liver	1/20
lung	3/75
lymphocyte	0/16
ovary	1/26
pancreas	4/24
peripheral nervous system	0/16
plasma cell	0/15
prostate	0/1
skin	1/24
soft tissue	0/9
thyroid	0/2
upper aerodigestive	5/22
urinary tract	0/29
uterus	0/5

Expression Distribution