WDR60

• Official Symbol: WDR60
• Official Name: WD repeat domain 60
• Aliases and Previous Symbols: N/A
• Entrez ID: 55112
• UniProt: Q8WVS4
• Interactions: BioGRID
• PubMed articles: Open PubMed
• OMIM: N/A

• Entrez Summary: This gene encodes a member of the WD repeat protein family. WD repeats are minimally conserved regions of approximately 40 amino acids typically bracketed by gly-his and trp-asp (GH-WD) and may facilitate the formation of heterotrimeric or multiprotein complexes. Members of this family are involved in a variety of cellular processes including cell cycle progression, signal transduction, apoptosis, and gene regulation. The encoded protein contains four WD repeats and may play a role in the formation of cilia. Mutations in this gene have been associated with short-rib polydactyly and Jeune syndromes. [provided by RefSeq, Mar 2014].
• UniProt Summary: May play a role in ciliogenesis. {ECO:0000269|PubMed:23910462}.

Pfam Domains GO Terms

Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)

• Essentiality Rank: 4863
• Expression level (log2 read counts): 4.89

Expression Distribution

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WDR60 Expression in NALM6 Cells: 4.89