ACTL8

Pfam Domains GO Terms

Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)

Global Fraction of Cell Lines Where Essential: 0/739

Tissue	Fraction Of Cell Lines Where Essential
1290807.0	0/1
909776.0	0/1
bile duct	0/28
blood	0/28
bone	0/26
breast	0/33
central nervous system	0/56
cervix	0/4
colorectal	0/17
esophagus	0/13
fibroblast	0/1
gastric	0/16
kidney	0/21
liver	0/20
lung	0/75
lymphocyte	0/16
ovary	0/26
pancreas	0/24
peripheral nervous system	0/16
plasma cell	0/15
prostate	0/1
skin	0/24
soft tissue	0/9
thyroid	0/2
upper aerodigestive	0/22
urinary tract	0/29
uterus	0/5

Expression Distribution

microtubule cortical anchor activity
nuclear migration along microtubule
dynactin complex
cell cortex region
nuclear migration
nucleus localization
establishment of mitotic spindle orientation
establishment of mitotic spindle localization
establishment of spindle orientation
establishment of spindle localization
spindle localization
organelle transport along microtubule
microtubule cytoskeleton organization involved in mitosis
establishment of cell polarity
transport along microtubule
cytoskeleton-dependent intracellular transport
microtubule-based transport
establishment or maintenance of cell polarity
microtubule-based movement
establishment of organelle localization
microtubule cytoskeleton organization
centrosome
organelle localization
mitotic cell cycle process
microtubule-based process
epithelial cell differentiation
mitotic cell cycle
cell cycle process
cytoskeleton organization
epithelium development
cell cycle
intracellular transport
movement of cell or subcellular component
tissue development
establishment of localization in cell