FADS1

Pfam Domains GO Terms

Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)

Screen	Score
∆-9-Tetrahydrocannabinol 30μM R08 exp445	-2.03
Quercetin 20μM R08 exp517	1.79
Dynasore 10μM R04 exp180	1.83
Dynasore 7μM R08 exp436	2.06
Tubacin 1.6μM R07 exp416	6.36

Global Fraction of Cell Lines Where Essential: 0/739

Tissue	Fraction Of Cell Lines Where Essential
1290807.0	0/1
909776.0	0/1
bile duct	0/28
blood	0/28
bone	0/26
breast	0/33
central nervous system	0/56
cervix	0/4
colorectal	0/17
esophagus	0/13
fibroblast	0/1
gastric	0/16
kidney	0/21
liver	0/20
lung	0/75
lymphocyte	0/16
ovary	0/26
pancreas	0/24
peripheral nervous system	0/16
plasma cell	0/15
prostate	0/1
skin	0/24
soft tissue	0/9
thyroid	0/2
upper aerodigestive	0/22
urinary tract	0/29
uterus	0/5

Expression Distribution

FA desaturase
Cyt-b5

acyl-CoA delta5-desaturase activity
omega-6 fatty acid desaturase activity
C-5 sterol desaturase activity
alpha-linolenic acid metabolic process
linoleic acid metabolic process
unsaturated fatty acid biosynthetic process
icosanoid biosynthetic process
fatty acid derivative biosynthetic process
unsaturated fatty acid metabolic process
icosanoid metabolic process
long-chain fatty acid metabolic process
fatty acid biosynthetic process
oxidoreductase activity
cellular response to starvation
fatty acid derivative metabolic process
monocarboxylic acid biosynthetic process
response to starvation
cellular response to nutrient levels
phospholipid biosynthetic process
cellular response to extracellular stimulus
carboxylic acid biosynthetic process
organic acid biosynthetic process
fatty acid metabolic process
cellular response to external stimulus
phospholipid metabolic process
regulation of lipid metabolic process
response to nutrient levels
drug metabolic process
monocarboxylic acid metabolic process
response to extracellular stimulus
organophosphate biosynthetic process
lipid biosynthetic process
small molecule biosynthetic process
intracellular membrane-bounded organelle
organophosphate metabolic process
carboxylic acid metabolic process
endoplasmic reticulum membrane
cellular lipid metabolic process
oxidation-reduction process
oxoacid metabolic process