KCNH7
Gene Information
- Official Symbol: KCNH7
- Official Name: potassium voltage-gated channel subfamily H member 7
- Aliases and Previous Symbols: N/A
- Entrez ID: 90134
- UniProt: Q9NS40
- Interactions: BioGRID
- PubMed articles: Open PubMed
- OMIM: Open OMIM
Function Summary
- Entrez Summary: Voltage-gated potassium (Kv) channels represent the most complex class of voltage-gated ion channels from both functional and structural standpoints. Their diverse functions include regulating neurotransmitter release, heart rate, insulin secretion, neuronal excitability, epithelial electrolyte transport, smooth muscle contraction, and cell volume. This gene encodes a member of the potassium channel, voltage-gated, subfamily H. This member is a pore-forming (alpha) subunit. There are at least two alternatively spliced transcript variants derived from this gene and encoding distinct isoforms. [provided by RefSeq, Jul 2008].
- UniProt Summary: Pore-forming (alpha) subunit of voltage-gated potassium channel. Channel properties may be modulated by cAMP and subunit assembly.
CRISPR Data
Essentiality in NALM6
- Essentiality Rank: 11204
- Expression level (log2 read counts): -3.59