SYT10

• Official Symbol: SYT10
• Official Name: synaptotagmin 10
• Aliases and Previous Symbols: N/A
• Entrez ID: 341359
• UniProt: Q6XYQ8
• Interactions: BioGRID
• PubMed articles: Open PubMed
• OMIM: N/A

• Entrez Summary: N/A
• UniProt Summary: Ca(2+) sensor specifically required for the Ca(2+)- dependent exocytosis of secretory vesicles containing IGF1 in neurons of the olfactory bulb. Exocytosis of IGF1 is required for sensory perception of smell. Not involved in Ca(2+)-dependent synaptic vesicle exocytosis (By similarity). Acts through Ca(2+) and phospholipid binding to the C2 domain: Ca(2+) induces binding of the C2-domains to phospholipid membranes and to assembled SNARE-complexes; both actions contribute to triggering exocytosis (By similarity). {ECO:0000250|UniProtKB:O08625, ECO:0000250|UniProtKB:Q9R0N4}.

Pfam Domains GO Terms

Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)

• Essentiality Rank: 6456
• Expression level (log2 read counts): -2.64

Expression Distribution

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SYT10 Expression in NALM6 Cells: -2.64