Sulforaphane 9μM R08 exp525
Mechanism of Action
Organosulfur compound, found in cruciferous plants
- Class / Subclass 1: Uncharacterized Mechanism / Natural Product
Technical Notes
Compound References
- PubChem Name: Sulforaphane
- Synonyms: N/A
- CAS #: 4478-93-7
- PubChem CID: 5350
- IUPAC: 1-isothiocyanato-4-methylsulfinylbutane
- INCHI Name: InChI=1S/C6H11NOS2/c1-10(8)5-3-2-4-7-6-9/h2-5H2,1H3
- INCHI Key: SUVMJBTUFCVSAD-UHFFFAOYSA-N
- Molecular Weight: 177.3
- Canonical SMILES: CS(=O)CCCCN=C=S
- Isomeric SMILES: N/A
- Molecular Formula: C6H11NOS2
Compound Supplier
- Supplier Name: Toronto Research Chemicals
- Catalog #: S699115
- Lot #: 5-YMK-45-1
Compound Characterization
- HRMS (ESI-TOF) m/z: (M+Na)+ Calcd for C6H11NOS2 200.01743; found 200.01687
Dose Response Curve
- Platform ID: Sulforaphane
- Min: -21.7878; Max: 99.8167
| IC | Concentration (µM) |
|---|---|
| IC10 | 8.1350 |
| IC20 | 8.8770 |
| IC30 | 9.4080 |
| IC40 | 9.8670 |
| IC50 | 10.3100 |
| IC60 | 10.7700 |
| IC70 | 11.2900 |
| IC80 | 11.9700 |
| IC90 | 13.0600 |
Screen Summary
- Round: 08
- Dose: 9µM
- Days of incubation: 8
- Doublings: 0.9
- Numbers of reads: 17245876
Screen Results
| Sensitive/Resistant hits (FDR<0.05) | CRANKS | Score Plot | Top 30 Genes | Screen Similarity | Top 30 Sensitive GO terms | Top 30 Resistant GO terms |
|---|---|---|---|---|---|---|
| 2/24 | Scores |