TIPARP

Gene Information
  • Official Symbol: TIPARP
  • Official Name: TCDD inducible poly(ADP-ribose) polymerase
  • Aliases and Previous Symbols: N/A
  • Entrez ID: 25976
  • UniProt: Q7Z3E1
  • Interactions: BioGRID
  • PubMed articles: Open PubMed
  • OMIM: Open OMIM
Function Summary
  • Entrez Summary: N/A
  • UniProt Summary: Poly [ADP-ribose] polymerase using NAD(+) as a substrate to transfer ADP-ribose onto glutamic acid residues of a protein acceptor; repeated rounds of ADP-ribosylation leads to the formation of poly(ADPribose) chains on the protein, thereby altering the function of the target protein. May play a role in the adaptive response to chemical exposure (TCDD) and thereby mediates certain effects of the chemicals (By similarity). {ECO:0000250}.

Pfam Domains GO Terms


CRISPR Data

Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)

Essentiality in NALM6
  • Essentiality Rank: 17431
  • Expression level (log2 read counts): 4.27

Expression Distribution

  • Last modified: 2025/12/10 20:19
  • by 127.0.0.1