ACOT11

Entrez Summary: N/A
UniProt Summary: Has acyl-CoA thioesterase activity towards medium (C12) and long-chain (C18) fatty acyl-CoA substrates.

Pfam Domains GO Terms

Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)

Global Fraction of Cell Lines Where Essential: 0/739

Tissue	Fraction Of Cell Lines Where Essential
1290807.0	0/1
909776.0	0/1
bile duct	0/28
blood	0/28
bone	0/26
breast	0/33
central nervous system	0/56
cervix	0/4
colorectal	0/17
esophagus	0/13
fibroblast	0/1
gastric	0/16
kidney	0/21
liver	0/20
lung	0/75
lymphocyte	0/16
ovary	0/26
pancreas	0/24
peripheral nervous system	0/16
plasma cell	0/15
prostate	0/1
skin	0/24
soft tissue	0/9
thyroid	0/2
upper aerodigestive	0/22
urinary tract	0/29
uterus	0/5

Expression Distribution

START
4HBT

palmitic acid metabolic process
palmitic acid biosynthetic process
long-chain fatty acyl-CoA binding
myristoyl-CoA hydrolase activity
palmitoyl-CoA hydrolase activity
acyl-CoA hydrolase activity
fatty-acyl-CoA binding
long-chain fatty acid biosynthetic process
carboxylic ester hydrolase activity
negative regulation of cold-induced thermogenesis
response to cold
thioester metabolic process
acyl-CoA metabolic process
long-chain fatty acid metabolic process
fatty acid biosynthetic process
ribonucleoside bisphosphate metabolic process
purine nucleoside bisphosphate metabolic process
nucleoside bisphosphate metabolic process
regulation of cold-induced thermogenesis
lipid binding
response to temperature stimulus
monocarboxylic acid biosynthetic process
coenzyme metabolic process
carboxylic acid biosynthetic process
organic acid biosynthetic process
purine ribonucleotide metabolic process
fatty acid metabolic process
ribonucleotide metabolic process
purine nucleotide metabolic process
ribose phosphate metabolic process
sulfur compound metabolic process
purine-containing compound metabolic process
mitochondrial matrix
cofactor metabolic process
nucleotide metabolic process
nucleoside phosphate metabolic process
monocarboxylic acid metabolic process
nucleobase-containing small molecule metabolic process
lipid biosynthetic process
small molecule biosynthetic process