AQP2

• Official Symbol: AQP2
• Official Name: aquaporin 2
• Aliases and Previous Symbols: N/A
• Entrez ID: 359
• UniProt: P41181
• Interactions: BioGRID
• PubMed articles: Open PubMed
• OMIM: Open OMIM

• Entrez Summary: This gene encodes a water channel protein located in the kidney collecting tubule. It belongs to the MIP/aquaporin family, some members of which are clustered together on chromosome 12q13. Mutations in this gene have been linked to autosomal dominant and recessive forms of nephrogenic diabetes insipidus. [provided by RefSeq, Oct 2008].
• UniProt Summary: Forms a water-specific channel that provides the plasma membranes of renal collecting duct with high permeability to water, thereby permitting water to move in the direction of an osmotic gradient.

Pfam Domains GO Terms

Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)

• Essentiality Rank: 10879
• Expression level (log2 read counts): -7.68

Expression Distribution

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AQP2 Expression in NALM6 Cells: -7.68