BLZF1

Entrez Summary: N/A
UniProt Summary: Required for normal Golgi structure and for protein transport from the endoplasmic reticulum (ER) through the Golgi apparatus to the cell surface.

Pfam Domains GO Terms

Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)

Global Fraction of Cell Lines Where Essential: 0/739

Tissue	Fraction Of Cell Lines Where Essential
1290807.0	0/1
909776.0	0/1
bile duct	0/28
blood	0/28
bone	0/26
breast	0/33
central nervous system	0/56
cervix	0/4
colorectal	0/17
esophagus	0/13
fibroblast	0/1
gastric	0/16
kidney	0/21
liver	0/20
lung	0/75
lymphocyte	0/16
ovary	0/26
pancreas	0/24
peripheral nervous system	0/16
plasma cell	0/15
prostate	0/1
skin	0/24
soft tissue	0/9
thyroid	0/2
upper aerodigestive	0/22
urinary tract	0/29
uterus	0/5

Expression Distribution

Screen	Score
Q15 2.7μM R02 exp79	-1.77
Clomiphene 4.4μM R02 exp68	-1.72

Golgi to plasma membrane protein transport
establishment of protein localization to plasma membrane
Golgi to plasma membrane transport
vesicle-mediated transport to the plasma membrane
post-Golgi vesicle-mediated transport
Golgi organization
protein localization to plasma membrane
protein localization to cell periphery
establishment of protein localization to membrane
ubiquitin protein ligase binding
enzyme binding
Golgi vesicle transport
regulation of cell growth
endomembrane system organization
protein localization to membrane
Golgi membrane
regulation of growth
DNA-binding transcription factor activity
Golgi apparatus
DNA binding
protein transport
peptide transport
amide transport
cellular protein localization
cellular macromolecule localization
establishment of protein localization
nitrogen compound transport
vesicle-mediated transport