C9orf3

Gene Information
  • Official Symbol: AOPEP
  • Official Name: aminopeptidase O (putative)
  • Aliases and Previous Symbols: N/A
  • Entrez ID: 84909
  • UniProt: Q8N6M6
  • Interactions: BioGRID
  • PubMed articles: Open PubMed
  • OMIM: Open OMIM
Function Summary
  • Entrez Summary: N/A
  • UniProt Summary: Aminopeptidases catalyze the hydrolysis of amino acid residues from the N-terminus of peptide or protein substrates. Able to cleave angiotensin III to generate angiotensin IV, a bioactive peptide of the renin-angiotensin pathway. Not able to cleave angiotensin I and angiotensin II. May play a role in the proteolytic processing of bioactive peptides in tissues such as testis and heart. {ECO:0000269|PubMed:15687497}.

Pfam Domains GO Terms


CRISPR Data

Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)

Essentiality in NALM6
  • Essentiality Rank: 16850
  • Expression level (log2 read counts): 3.86

Expression Distribution

  • Last modified: 2026/01/07 22:36
  • by 127.0.0.1