CCDC23

Entrez Summary: N/A
UniProt Summary: Enhances the solubility and secretion of VASH1 and prevents its ubiquitination. Also enhances secretion of VASH2. {ECO:0000269|PubMed:20736312}.

Pfam Domains GO Terms

Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)

Global Fraction of Cell Lines Where Essential: 0/739

Tissue	Fraction Of Cell Lines Where Essential
1290807.0	0/1
909776.0	0/1
bile duct	0/28
blood	0/28
bone	0/26
breast	0/33
central nervous system	0/56
cervix	0/4
colorectal	0/17
esophagus	0/13
fibroblast	0/1
gastric	0/16
kidney	0/21
liver	0/20
lung	0/75
lymphocyte	0/16
ovary	0/26
pancreas	0/24
peripheral nervous system	0/16
plasma cell	0/15
prostate	0/1
skin	0/24
soft tissue	0/9
thyroid	0/2
upper aerodigestive	0/22
urinary tract	0/29
uterus	0/5

Expression Distribution

negative regulation of endothelial cell migration
negative regulation of epithelial cell migration
apical part of cell
negative regulation of protein ubiquitination
negative regulation of protein modification by small protein conjugation or removal
regulation of endothelial cell migration
protein secretion
establishment of protein localization to extracellular region
protein localization to extracellular region
peptide secretion
regulation of protein ubiquitination
regulation of epithelial cell migration
regulation of protein modification by small protein conjugation or removal
negative regulation of cell migration
negative regulation of cell motility
negative regulation of cellular component movement
negative regulation of locomotion
negative regulation of protein modification process
regulation of cell migration
regulation of cell motility
regulation of locomotion
regulation of cellular component movement
secretion by cell
negative regulation of cellular protein metabolic process
export from cell
negative regulation of protein metabolic process
secretion
negative regulation of multicellular organismal process
proteolysis
protein transport
peptide transport
amide transport
establishment of protein localization
regulation of protein modification process
nitrogen compound transport
extracellular region