CLPS

Entrez Summary: N/A
UniProt Summary: Colipase is a cofactor of pancreatic lipase. It allows the lipase to anchor itself to the lipid-water interface. Without colipase the enzyme is washed off by bile salts, which have an inhibitory effect on the lipase.

Pfam Domains GO Terms

Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)

Global Fraction of Cell Lines Where Essential: 1/739

Tissue	Fraction Of Cell Lines Where Essential
1290807.0	0/1
909776.0	0/1
bile duct	0/28
blood	0/28
bone	0/26
breast	0/33
central nervous system	0/56
cervix	0/4
colorectal	0/17
esophagus	0/13
fibroblast	0/1
gastric	0/16
kidney	0/21
liver	0/20
lung	0/75
lymphocyte	0/16
ovary	0/26
pancreas	0/24
peripheral nervous system	1/16
plasma cell	0/15
prostate	0/1
skin	0/24
soft tissue	0/9
thyroid	0/2
upper aerodigestive	0/22
urinary tract	0/29
uterus	0/5

Expression Distribution

lipid digestion
response to food
enzyme activator activity
retinoid metabolic process
diterpenoid metabolic process
digestion
terpenoid metabolic process
isoprenoid metabolic process
lipid catabolic process
response to nutrient levels
response to extracellular stimulus
response to bacterium
cellular lipid metabolic process
lipid metabolic process
response to other organism
response to external biotic stimulus
response to biotic stimulus
positive regulation of catalytic activity
organic substance catabolic process
positive regulation of molecular function
extracellular region