DOCK7

• Official Symbol: DOCK7
• Official Name: dedicator of cytokinesis 7
• Aliases and Previous Symbols: N/A
• Entrez ID: 85440
• UniProt: Q96N67
• Interactions: BioGRID
• PubMed articles: Open PubMed
• OMIM: Open OMIM

• Entrez Summary: The protein encoded by this gene is a guanine nucleotide exchange factor (GEF) that plays a role in axon formation and neuronal polarization. The encoded protein displays GEF activity toward RAC1 and RAC3 Rho small GTPases but not toward CDC42. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2012].
• UniProt Summary: N/A

Pfam Domains GO Terms

Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)

• Essentiality Rank: 5969
• Expression level (log2 read counts): 5.61

Expression Distribution

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DOCK7 Expression in NALM6 Cells: 5.61