EFCAB9

Pfam Domains GO Terms

Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)

Screen	Score
Golgicide-A 4μM R03 exp122	1.7
2-Methoxyestradiol 0.55μM R07 exp310	1.77
Cycloheximide 0.02μM R00 exp14	1.78
Pyronaridine 1μM R06 exp295	1.86
2-Methoxyestradiol 0.55 to 0.75μM on day4 R07 exp311	2.16

Global Fraction of Cell Lines Where Essential: 0/739

Tissue	Fraction Of Cell Lines Where Essential
1290807.0	0/1
909776.0	0/1
bile duct	0/28
blood	0/28
bone	0/26
breast	0/33
central nervous system	0/56
cervix	0/4
colorectal	0/17
esophagus	0/13
fibroblast	0/1
gastric	0/16
kidney	0/21
liver	0/20
lung	0/75
lymphocyte	0/16
ovary	0/26
pancreas	0/24
peripheral nervous system	0/16
plasma cell	0/15
prostate	0/1
skin	0/24
soft tissue	0/9
thyroid	0/2
upper aerodigestive	0/22
urinary tract	0/29
uterus	0/5

Expression Distribution

calcium ion sensor activity
sperm principal piece
sperm capacitation
flagellated sperm motility
sperm motility
cilium-dependent cell motility
cilium or flagellum-dependent cell motility
spermatid development
spermatid differentiation
cell maturation
developmental maturation
germ cell development
cellular process involved in reproduction in multicellular organism
spermatogenesis
male gamete generation
developmental process involved in reproduction
gamete generation
calcium ion binding
multicellular organismal reproductive process
sexual reproduction
multicellular organism reproduction
multi-organism reproductive process
localization of cell
cell motility
locomotion
reproductive process
reproduction
movement of cell or subcellular component
cell development