FAM132B

Gene Information
Function Summary
  • Entrez Summary: N/A
  • UniProt Summary: Iron-regulatory hormone that acts as an erythroid regulator after hemorrhage: produced by erythroblasts following blood loss and mediates suppression of hepcidin (HAMP) expression in the liver, thereby promoting increased iron absorption and mobilization from stores. Promotes lipid uptake into adipocytes and hepatocytes via transcriptional up-regulation of genes involved in fatty acid uptake. {ECO:0000250|UniProtKB:Q6PGN1}.

Pfam Domains GO Terms


CRISPR Data

Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)

Essentiality in NALM6
  • Essentiality Rank: 13442
  • Expression level (log2 read counts): -0.23

Expression Distribution

  • Last modified: 2026/01/07 22:36
  • by 127.0.0.1