GABPB1

Gene Information
  • Official Symbol: GABPB1
  • Official Name: GA binding protein transcription factor subunit beta 1
  • Aliases and Previous Symbols: N/A
  • Entrez ID: 2553
  • UniProt: Q06547
  • Interactions: BioGRID
  • PubMed articles: Open PubMed
  • OMIM: Open OMIM
Function Summary
  • Entrez Summary: This gene encodes the GA-binding protein transcription factor, beta subunit. This protein forms a tetrameric complex with the alpha subunit, and stimulates transcription of target genes. The encoded protein may be involved in activation of cytochrome oxidase expression and nuclear control of mitochondrial function. The crystal structure of a similar protein in mouse has been resolved as a ternary protein complex. Multiple transcript variants encoding distinct isoforms have been identified for this gene. [provided by RefSeq, Jul 2008].
  • UniProt Summary: Transcription factor capable of interacting with purine rich repeats (GA repeats). Necessary for the expression of the Adenovirus E4 gene. {ECO:0000269|PubMed:10675337, ECO:0000269|PubMed:8816484}.

Pfam Domains GO Terms


CRISPR Data

Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)

Essentiality in NALM6
  • Essentiality Rank: 829
  • Expression level (log2 read counts): 6.08

Expression Distribution

  • Last modified: 2025/12/10 20:19
  • by 127.0.0.1