GAD2

Pfam Domains GO Terms

Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)

Global Fraction of Cell Lines Where Essential: 0/739

Tissue	Fraction Of Cell Lines Where Essential
1290807.0	0/1
909776.0	0/1
bile duct	0/28
blood	0/28
bone	0/26
breast	0/33
central nervous system	0/56
cervix	0/4
colorectal	0/17
esophagus	0/13
fibroblast	0/1
gastric	0/16
kidney	0/21
liver	0/20
lung	0/75
lymphocyte	0/16
ovary	0/26
pancreas	0/24
peripheral nervous system	0/16
plasma cell	0/15
prostate	0/1
skin	0/24
soft tissue	0/9
thyroid	0/2
upper aerodigestive	0/22
urinary tract	0/29
uterus	0/5

Expression Distribution

glutamate decarboxylation to succinate
glutamate decarboxylase activity
clathrin-sculpted gamma-aminobutyric acid transport vesicle membrane
glutamate catabolic process
glutamate binding
inhibitory synapse
dicarboxylic acid catabolic process
glutamine family amino acid catabolic process
glutamate metabolic process
neurotransmitter biosynthetic process
pyridoxal phosphate binding
synaptic vesicle membrane
glutamine family amino acid metabolic process
presynaptic membrane
neurotransmitter metabolic process
dicarboxylic acid metabolic process
anchored component of membrane
neurotransmitter secretion
signal release from synapse
alpha-amino acid catabolic process
cellular amino acid catabolic process
signal release
neurotransmitter transport
alpha-amino acid metabolic process
carboxylic acid catabolic process
organic acid catabolic process
axon
cellular amino acid metabolic process
regulation of neurotransmitter levels
anterograde trans-synaptic signaling
chemical synaptic transmission
trans-synaptic signaling
small molecule catabolic process
synaptic signaling
protein heterodimerization activity
cell junction
Golgi membrane
perinuclear region of cytoplasm
carboxylic acid metabolic process
oxoacid metabolic process