GOLPH3L

Entrez Summary: N/A
UniProt Summary: Phosphatidylinositol-4-phosphate-binding protein that may antagonize the action of GOLPH3 which is required for the process of vesicle budding at the Golgi and anterograde transport to the plasma membrane. {ECO:0000269|PubMed:23345592}.

Pfam Domains GO Terms

Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)

Global Fraction of Cell Lines Where Essential: 0/739

Tissue	Fraction Of Cell Lines Where Essential
1290807.0	0/1
909776.0	0/1
bile duct	0/28
blood	0/28
bone	0/26
breast	0/33
central nervous system	0/56
cervix	0/4
colorectal	0/17
esophagus	0/13
fibroblast	0/1
gastric	0/16
kidney	0/21
liver	0/20
lung	0/75
lymphocyte	0/16
ovary	0/26
pancreas	0/24
peripheral nervous system	0/16
plasma cell	0/15
prostate	0/1
skin	0/24
soft tissue	0/9
thyroid	0/2
upper aerodigestive	0/22
urinary tract	0/29
uterus	0/5

Expression Distribution

Golgi cisterna
phosphatidylinositol-4-phosphate binding
Golgi to plasma membrane protein transport
establishment of protein localization to plasma membrane
Golgi to plasma membrane transport
Golgi vesicle budding
retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum
Golgi cisterna membrane
vesicle-mediated transport to the plasma membrane
trans-Golgi network membrane
vesicle budding from membrane
post-Golgi vesicle-mediated transport
Golgi organization
trans-Golgi network
protein localization to plasma membrane
protein localization to cell periphery
establishment of protein localization to membrane
positive regulation of protein secretion
positive regulation of peptide secretion
vesicle organization
Golgi vesicle transport
positive regulation of secretion by cell
endomembrane system organization
positive regulation of protein transport
positive regulation of secretion
positive regulation of establishment of protein localization
regulation of protein secretion
protein localization to membrane
regulation of peptide secretion
Golgi membrane
regulation of protein transport
regulation of peptide transport
regulation of establishment of protein localization
regulation of secretion by cell
regulation of secretion
membrane organization
positive regulation of transport
regulation of protein localization
protein transport
peptide transport