GOLT1B

Entrez Summary: N/A
UniProt Summary: May be involved in fusion of ER-derived transport vesicles with the Golgi complex.

Pfam Domains GO Terms

Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)

Screen	Score
NFN1 0.1μM R01 exp49	-2.48
Cerivastatin 0.15μM R05 exp226	-1.83
2-Methoxyestradiol 0.2μM R01 exp40	-1.74
Zebularine 20μM R07 exp423	-1.74
CyclicAMP 200μM R08 exp475	-1.73
Pimelic-diphenylamide-106 5μM R00 exp28	1.76
Nicotine 3000μM R08 exp510	1.82

Global Fraction of Cell Lines Where Essential: 0/739

Tissue	Fraction Of Cell Lines Where Essential
1290807.0	0/1
909776.0	0/1
bile duct	0/28
blood	0/28
bone	0/26
breast	0/33
central nervous system	0/56
cervix	0/4
colorectal	0/17
esophagus	0/13
fibroblast	0/1
gastric	0/16
kidney	0/21
liver	0/20
lung	0/75
lymphocyte	0/16
ovary	0/26
pancreas	0/24
peripheral nervous system	0/16
plasma cell	0/15
prostate	0/1
skin	0/24
soft tissue	0/9
thyroid	0/2
upper aerodigestive	0/22
urinary tract	0/29
uterus	0/5

Expression Distribution

positive regulation of I-kappaB kinase/NF-kappaB signaling
regulation of I-kappaB kinase/NF-kappaB signaling
protein-containing complex
Golgi membrane
endoplasmic reticulum
positive regulation of intracellular signal transduction
protein transport
peptide transport
amide transport
establishment of protein localization
positive regulation of signal transduction
positive regulation of cell communication
positive regulation of signaling
regulation of intracellular signal transduction
nitrogen compound transport
vesicle-mediated transport
membrane