GPR115

Gene Information
  • Official Symbol: ADGRF4
  • Official Name: adhesion G protein-coupled receptor F4
  • Aliases and Previous Symbols: N/A
  • Entrez ID: 221393
  • UniProt: Q8IZF3
  • Interactions: BioGRID
  • PubMed articles: Open PubMed
  • OMIM: Open OMIM
Function Summary
  • Entrez Summary: Sequence analysis of this gene suggests that it is encodes a member of the superfamily of G protein-couple receptors. G protein-coupled receptors typically contain seven hydrophobic transmembrane domains, interact with guanine nucleotide binding regulatory proteins, and detect molecules outside the cell and act to transduce these signals into intracellular responses. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2016].
  • UniProt Summary: Orphan receptor.

Pfam Domains GO Terms


CRISPR Data

Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)

Essentiality in NALM6
  • Essentiality Rank: 18221
  • Expression level (log2 read counts): -5.6

Expression Distribution

  • Last modified: 2026/01/07 22:36
  • by 127.0.0.1